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July 2016 – New Drug Approvals
For example, a wide range of acids may be used, including but not limited to phosphoric acid, trifluoroacetic acid, p-toluenesulfonic acid, methanesulfonic acid, ethanesulfonic acid, benzenesulfonic acid, p-toluenesulfonic acid, 4-bromobenzenesulfonic acid, thionyl chloride,and trimethylsilyl chloride.
US Patent for Substituted diaminocarboxamide and .
Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.
Hydrazide conjugates as imaging agents - Free Patents Online
Jan 18, 2007· The present disclosure is directed to diagnostic agents. More specifically, the disclosure is directed to compounds, diagnostic agents, compositions, and kits for detecting and/or
US4148801A - 3-[(Chlorophenylsulfonyl)methyl]-1,2,4 .
US4148801A US05/921,293 US92129378A US4148801A US 4148801 A US4148801 A US 4148801A US 92129378 A US92129378 A US 92129378A US 4148801 A US4148801 A US 4148801A Authority US United States Prior art keywords ch carboxylic acid chlorophenylsulfonyl compound oxadiazole Prior art date 1978-07-03 Legal status (The legal status is an assumption and is not a legal conclusion.
Mtor kinase inhibitors for oncological indications and .
FIELD: medicine, pharmaceutics. SUBSTANCE: in general formulas R 1 represents substituted phenyl, substituted or unsubstituted heterocyclyl, which represents an aromatic cycloalky
US Patent for Somatostatin receptor subtype 4 (SSTR4 .
3-aza-bicyclo[3.1.0]hexane-6-carboxylic acid amide derivatives which are agonists of somatostatin receptor subtype 4 (SSTR4), useful for preventing or treating medical disorders related to SSTR4.
Dataset - DrugBank Drug Targets - Ma'ayan Laboratory
Search for genes and functional terms extracted and organized from over a hundred publicly available resources.
Functional Microgels and Microgel Systems | Accounts of .
ConspectusMicrogels are macromolecular networks swollen by the solvent in which they are dissolved. They are unique systems that are distinctly different from common colloids, such as, e.g., rigid nanoparticles, flexible macromolecules, micelles, or vesicles. The size of the microgel networks is in the range of several micrometers down to nanometers (then sometimes called "nanogels").
September « 2019 « New Drug Approvals
Nilotinib base (1 g) was suspended in water (20 ml). A solution of benzenesulfonic acid (0.4 g) in water (3ml) was added and the content was heated at 60 °C for 2-3 h. The mixture was cooled to 25-30 °C, filtered, washed with water (3 x 5 ml) and dried under vacuum for 2 h at 50-55 °C.
EP2431362A1 - 3-(4-aminophenyl)-2-furancarboxylic acid .
Disclosed is a compound represented by Formula (I) or a pharmaceutically acceptable salt thereof: wherein R 1 is 1: a C 3-8 cycloalkyl C 1-4 alkyl group, 2: a C 7-14 aralkyl group, in which the aryl moiety thereof is optionally substituted with the same or different 1 to 3 groups selected from the group consisting of: (a) halogen, (b) C 1-4 alkyl, which is optionally substituted with 1 to 3 .