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    The wonders of 2-deoxy-d-glucose. Authors. Haibin Xi, Department of Microbiology, Immunology and Molecular Genetics, and Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California Los Angeles, Los Angeles, CA, USA; Search for more papers by this author.

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    2-Deoxy-D-glucose - Wikipedia

    2-Deoxy-d-glucose is a glucose molecule which has the 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis. As such; it acts to competitively inhibit the production of glucose-6-phosphate from glucose at the phosphoglucoisomerase level (step 2 of glycolysis).

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    2-Deoxy-D-glucose ≥99% (GC), crystalline | Sigma-Aldrich

    2-Deoxy-D-Glucose (2-Deoxyglucose) is a glucose analog that inhibits glycolysis via its actions on hexokinase, the rate limiting step of glycolysis. It is phosphorylated by hexokinase to 2-DG-P which can not be further metabolized by phosphoglucose isomerase. This leads to the accumulation of 2-DG-P in the cell and the depletion in cellular ATP.

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    2-Deoxy-D-glucose is used is a natural anti-metabolite antibiotic with a variety of physiological and pharmacological effects such as inhibiting infection, yeast fermentation, pathogenic bacteria and growth of tumor cells.It has anti-bacterial, anti-cancer, anti-epilepsy and other functions, and is used to prevent pathogenic bacteria infection .

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    2 Deoxy D Glucose - Buy 2 Deoxy D Glucose Product on .

    Our production 2-Deoxy-D-Glucose appears white crystal powder. Specific Rotation is 47°±1 and its content is above 98%. It has been used widely to inhibit herpes simplex and fluenza, RNA DNA enveloped viruses etc. 2-Deoxy-D-Glucose is a new natural antibiotics. It can inhibit the growth of various pathogenic microorganism.

    2-Deoxy-D-glucose Supplier | CAS 154-17-6 | Tocris Bioscience

    1 Citation for 2-Deoxy-D-glucose. Citations are publications that use Tocris products. Selected citations for 2-Deoxy-D-glucose include: Lin et al (2017) Lactate-activated macrophages induced aerobic glycolysis and epithelial-mesenchymal transition in breast cancer by regulation of CCL5-CCR5 axis: a positive metabolic feedback loop.

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    High Quality 2-deoxy-d-glucose Cas 154-17-6 - Buy 2-deoxy .

    Mar 20, 2019· High quality 2-Deoxy-D-glucose CAS 154-17-6. Application: 2-deoxy-d-glucose (2-dg) is a natural anti-metabolite antibiotic, which can inhibit viral infection, yeast fermentation, pathogenic bacteria and tumor cell growth.

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    2-Deoxy-D-glucose (CAS 154-17-6): R&D Systems

    Greater cell cycle inhibition and cytotoxicity induced by 2-deoxy-D-glucose in tumor cells treated under hypoxic vs aerobic conditions. Maher et al. Cancer Chemother.Pharmacol., 2004;53:116 A catabolic block does not sufficiently explain how 2-deoxy- D -glucose inhibits cell growth.

    2-Deoxy-D-glucose - chemeurope

    2-Deoxy-D-glucose is a glucose molecule which has the 2-hydroxyl group replaced by hydrogen, so that it cannot undergo further glycolysis. Glucose hexokinase traps this substance in most cells (with exception of liver and kidney) so that it makes a good marker for …

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    2-Deoxy-D-Glucose (2dg) | mcrc4

    2-Deoxy-D-Glucose (2dg) Posted on July 10, 2013 by Ren. 2DG is a funky molecule that I came across last month and have started taking it last week as an IV infusion. 2DG is a modified version of Glucose having a hydroxyl group replaced with hydrogen. The simple modification means that it can not undergo glycolysis, the fermentation step used by .

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